Alpha-2 - Veterinary Services

Alpha-2 EQ – Alpha-2 Macroglobulin orthobiologic therapy

Alpha-2 Macroglobulin (α2M), is the body’s natural defence against cartilage breakdown, joint pain and inflammation. Found naturally in the horse’s bloodstream, this molecule is too large to enter joint spaces in effective quantities. However, using the Alpha2EQ orthobiologic device, a2M can be processed at the yard, concentrated at up to 5 times naturally occurring levels, and injected into joints. It prevents cartilage breakdown, capturing and eliminating destructive enzymes in the joint space, and thereby slowing the progression of osteoarthritis and degenerative joint disease. This procedure delivers the highest level of a2M available on the market today and has been proven to successfully decrease inflammation, relieve pain and modulate cartilage degeneration caused by osteoarthritis.

The procedure is relatively simple and minimally invasive. First, a blood sample is collected from your horse. This is processed, centrifuged and filtered using the special Alpha2EQ equipment, isolating the a2M molecules and concentrating them into an injectable plasma. This is then injected into required areas (like a standard joint injection procedure). If required, excess a2M plasma can be frozen for future use. The results of treatment can be observed within a few days and have long-lasting effects of 6 – 12 months.

Alpha2EQ helps treat inflammation and can be used as a pretreatment for other regenerative therapies such as PRP and Stem Cells. Derived from the horse itself, as a naturally occurring biological substance it can help the healing of fractured bones as well as injured muscles, tendons and ligaments. There are no known long-term risks of Alpha2EQ therapy. It is also safe to use in joints that have previously been injected with other biologics or steroids. Also, as it is drug-free, Alpha2EQ contains no prohibited substances, making it ideal for competition/performance horses at any level.

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